Targeting sepsis, the leading cause of ICU deaths, with a nanocarrier-delivered microRNA

One obstacle to therapeutic use of microRNAs (miRNA), which are in clinical trial for a number of diseases, are ribonucleases, whose job it is to destroy them. Researchers report that an miRNA (miR-126) protective against sepsis can be delivered effectively via a nanocarrier. Almost 67 percent of mice treated with one of the nanocarrier/miR-126 complexes were still alive at seven days vs. just 25 percent of controls.

from Engineering and Construction News – ScienceDaily https://www.sciencedaily.com/releases/2018/12/181203115430.htm

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